百合地黄汤为临床常用中药经方，组方相对简单，临床应用广泛，古代常用来治疗百合病，现代临床主要用于治疗多种抑郁症（如阈下抑郁、产后抑郁、更年期抑郁等）、多种失眠症（如更年期失眠、老年失眠等）、焦虑症、心理亚健康等疾病。通过文献分析，归纳总结了百合地黄汤在神经精神系统中的临床应用与药理作用研究进展，以期为百合地黄汤的临床合理应用及现代药理作用机制研究提供参考。

Baihe Dihuang Decoction (BDD) is a Chinese materia medica compound, and the formulation is relatively simple and widespread in clinical application. In ancient times, it is commonly used to treat lily disease, but for modern clinical application it is mainly used for the treatment of a variety of depression (such as subliminal depression, postpartum depression, menopausal depression, etc.), a variety of insomnia (such as menopausal insomnia, intractable insomnia, old age insomnia, etc.) anxiety, suboptimal health and so on. In this paper, the clinical and pharmacological effects of BDD decoction in neuropsychiatric system were summarized by literature analysis, in order to provide a reference for the clinical rational application and the study of modern pharmacological mechanism of BDD.

山西省科技计划项目（201603D321077，201603D3113013，201601D011122，201701D22111344）；山西省科技创新重点团队（201605D131045-18）；山西省重点实验室（201605D111004）