目的 研究鹧鸪茶Mallotus furetianus树叶化学成分。方法 综合采用硅胶柱色谱、反相柱色谱及制备HPLC色谱等方法进行分离纯化，利用紫外、质谱及核磁共振谱等方法鉴定化合物的结构。结果 从鹧鸪茶叶50%乙醇提取物中分离得到了15个多酚类化合物和1个生物碱，分别鉴定为3-羟基-4，5（R）-二甲基-2（5H）-呋喃酮（1）、没食子酸（2）、3，4，8，9，10-五羟基二苯并[b，d]吡喃-6-酮（3）、表儿茶素（4）、儿茶素（5）、山柰酚-3-O-洋槐糖苷（6）、洋芹素（7）、2-羟基丁二酸（8）、5-羟甲基糠酸（9）、没食子酸甲酯（10）、咖啡酸（11）、丹参素（12）、diolmycin B2（13）、oresbiusin A（14）、3，4-二羟基苯基-β-D-吡喃葡萄糖苷（15）、焦谷氨酸（16）。结论 化合物7～16为首次从该属植物中分离得到，化合物4～16为首次从鹧鸪茶中分离得到。

Objective To study the chemical constituents of Mallotus furetianus. Methods The constituents were isolated and purified by silica gel chromatography and HPLC repeatedly, and the structures were identified by spectra analysis and chemical methods. Results Sixteen compounds were isolated from the leaves of M. furetianus, the structures were identified as 3-hydroxy-4,5 (R)-dimethy1-2 (5H)-furanone (1), gallic acid (2), 3,4,8,9,10-pentahydroxydibenzo[b, d] pyran-6-one (3), epicatechin (4), catechin (5), kaempferol-3-O-robinobioside (6), apigenin (7), 2-hydroxysuccinic acid (8), 5-hydroxymethylfuroic acid (9), gallic acid methyl ester (10), caffeic acid (11), tanshinol (12), diolmycin B2 (13), oresbiusin A (14), 3,4-dihydroxyphenyl-β-D-glucopyranoside (15), and (2S)-pyroglutamic acid (16). Conclusion Compounds 7-16 are obtained from the genus of Mallotus for the first time, and compounds 4-16 are obtained from M. furetianus for the first time.

海南省自然科学基金创新研究团队项目（2017CXTD022）；中央级公益性科研院所基本科研业务费专项（2013HNB02）