目的 研究水栀子Gardenia jasminosides var.radicans的酚性成分。方法 采用硅胶、Toyopearl HW-40、Sephadex LH-20、MCI gel CHP-20、ODS柱色谱法及制备液相进行分离纯化，根据理化性质和波谱数据鉴定化合物结构。结果 从水栀子醋酸乙酯部位分离得到17个酚性化合物，分别鉴定为3，3'，5-trimethoxy-9，9'-epoxylignane-4，4'-diol（1)、3，4-二香草酰基四氢呋喃（2)、marphenol C（3)、芥子醛（4)、对羟基肉桂酸（5)、异阿魏酸（6)、咖啡酸（7)、异秦皮啶（8)、异莨菪内酯（9)、6-甲氧基-7-羟基香豆素（10)、6，7-二羟基香豆素（11)、丁香酸（12)、3-羟基-4-甲氧基苯甲酸（13)、3，4-二羟基苯甲酸（14)、对羟基苯甲酸（15)、没食子酸-3-甲基醚（16)、没食子酸（17)。结论 以上化合物均为首次从水栀子中分离得到。

Objective To investigate the phenolic constituents in the fruit of Gardenia jasminosides var. radicans. Methods The phenolic constituents were isolated and identified by chromatography on silica gel, Toyopearl HW-40, Sephadex LH-20, MCI gel CHP-20, ODS, and RP-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analyses. Results Seventeen compounds were isolated from 50% aqueous acetone extract from the fruit of Gardenia jasminosides var. radicans and identified as 3,3',5-trimethoxy-9,9'-epoxylignane-4,4'-diol (1), 3,4-divanillyltetrahydrofuran (2), marphenol C (3), sinapaldehyde (4), hydroxycinnamic acid (5), isoferulic acid (6), caffeic acid (7), isofraxidin (8), isoscopoletin (9), 6-methoxy-7-hydroxycoumarin (10), 6,7-dihydroxycoumarin (11), syringic acid (12), 3-hydroxy-4-methoxybenzoic acid (13), 3,4-dihydroxybenzoic acid (14), p-hydroxybenzoate (15), 4,5-dihydroxy-3-methoxy-benzoic acid (16), and gallic acid (17). Conclusion All 17 compounds are isolated from this plant for the first time.

教育部科学技术研究重点资助项目（DF2003078）