目的 考察春、秋两采收期道地产区内蒙古阿拉善盟肉苁蓉Cistanche deserticola中松果菊苷、毛蕊花糖苷、半乳糖醇、甜菜碱、可溶性多糖及其浸出物的量，并研究其道地性。方法 采用HPLC-UV法测定松果菊苷及毛蕊花糖苷量，采用HPLC-ELSD法测定半乳糖醇及甜菜碱量，采用UV-VIS法测定可溶性多糖量，采用醇溶性浸出物测定法测定浸出物。结果 春季、秋季肉苁蓉中指标成分总量均达到《中国药典》2015年版规定水平，且春季的量较高，达12.21 mg/g，是秋季样品量的3倍多，为《中国药典》2015年版规定量的4倍。毛蕊花糖苷的量在春季样品显著高于秋季，约为秋季的30倍，波动极大；甜菜碱的量在春季样品中也显著高于秋季；可溶性多糖的量在春、秋季样品中均处于较高水平，尤其是秋季样品中高达13.7%；半乳糖醇及浸出物的量在秋季样品中显著高于春季。结论 肉苁蓉春季、秋季样品中毛蕊花糖苷量波动极大；本品含有丰富的可溶性多糖、半乳糖醇，而"油亮、体重、肥厚、质柔润、味甘"为肉苁蓉道地性内在品质特征，丰富的多糖、半乳糖醇是其品质形成的物质基础，可增加多糖作为评价其质量特征的指标成分之一。

Objective To investigate the contents of major five functional components (echinacoside, verbascoside, galactitol, betaine, soluble polysaccharide, and extractums) in Cistanche deserticola harvested in spring and autumn from genuine producing area in Alax Banner of Inner Mongolia. Methods HPLC-UV was applied to measuring the contents of echinacoside and verbascoside. HPLC-ELSD was used for determining the contents of galactitol and betaine. UV-VIS was utilized for analyzing the content of soluble polysaccharide. Results The index components of two samples' harvested in spring and autumn were all up to the standard of Chinese Pharmacopoeia. The samples harvested in spring contain 12.21 mg/g, which was twice of the autumn samples and fourfold of the standard of Chinese Pharmacopoeia. Based on verbascoside and betaine, the content of spring samples was significantly higher than the autumn samples, which was up to thirtyfold and it had great fluctuation among samples; Based on soluble polysaccharide, the content of spring and autumn samples were all at a high level, especially autumn samples was up to 13.7%; Based on galactitol and extractums, the content of autumn samples was significantly higher than the spring samples. Conclusion The content of verbascoside in C. deserticola has great fluctuation among samples. C. deserticola, that is rich in galactitol and soluble polysaccharide that authentic inner quality characteristics are "Glossy, Heavy, Fleshy, Quality soft, Sweet". Nevertheless, the ample galactitol and soluble polysaccharide is the material basis of quality formation, it is more reasonable to add the soluble polysaccharide as one of the index component to evaluate its quality characteristics. The standard of Chinese Pharmacopoeia points out the moisture limit of succulent herb is 10% may not be reasonable. The further improvement of the standard of C. deserticola's quality or separation of C. deserticola was discussed in this manuscript.

内蒙古自治区科技计划项目（NK20150168）；科技服务项目：天津引种中药材规范化培育的系统研究；科技服务项目：基于药效物质基础的精标饮片组分权重比整体质量控制体系建立的研究