肠道菌群作为人体内庞大的微生态系统，与人体健康状况有着密切的关联。其特点是数量大、种类多，一旦失调，将会引发各种疾病。中药对肠道菌群的稳态具有调节作用，同时肠道菌群对中药成分具有代谢转化作用，中药与肠道菌群的相互作用研究对实现中药现代化具有重要意义。对近年来关于肠道菌群与中药相互作用的研究成果进行整理归纳，为后续进一步深入研究中药与肠道菌群的关系提供参考。

There are a huge number of microorganisms in human intestinal, and they are closely related to human health. Their characteristics are huge amount and great variety, if the intestinal flora are imbalance, it could cause a variety of diseases. Traditional Chinese medicine can balance the intestinal flora, meanwhile intestinal flora can metabolize Chinese materia medica (CMM) to effective component. The research on CMM and the intestinal flora has great significance to realize the modernization of CMM. In this paper, we summarized the recent years' research reports and its achievements on the interaction of intestinal flora and CMM, and provide a reference for further research about the relationship of intestinal flora and CMM.

科技部重大新药创制：现代中药创新集群与数字制药技术平台（2013ZX09402203）