目的 研究膜荚黄芪Astragalus membranaceus 根的化学成分。方法 采用硅胶、ODS、聚酰胺、Sephadex LH-20等柱色谱方法对化合物进行分离，运用核磁共振波谱方法鉴定化合物的结构。结果 从膜荚黄芪根的乙醇提取物中分离得到23个化合物，包括14个黄酮类化合物：2'-methoxyisoliquiritigenin（1）、刺甘草查耳酮（2）、甘草查耳酮B（3）、3'，4'，7-trihydroxyflavone（4）、4'，7-dihydroxyflavone（5）、3'，7，8-trihydroxy-4'-methoxyisoflavone（6）、毛蕊异黄酮（8）、芒柄花素（9）、2'，4，4'-trihydroxychalcone（10）、pendulone（11）、liquiritigenin（12）、pratensein（13）、毛蕊异黄酮苷（14）、芒柄花苷（15），8个三萜皂苷类化合物：黄芪甲苷（16）、cyclocanthoside E（17）、异黄芪皂苷II（18）、黄芪皂苷II（19）、黄芪皂苷III（20）、异黄芪皂苷I（21）、brachyoside B（22）、cycloaraloside A（23）及1个苯丙酸类化合物：4-hydroxycinnamic acid（7）。结论 化合物1~7为首次从该属植物中分离得到。

Objective To study the chemical constituents in the roots of Astragalus membranaceus. Methods The constituents were isolated and purified by silica gel, ODS, polyamide and Sephadex LH-20 column chromatography. Their structures were elucidated by NMR spectra. Results Twenty-three compounds were isolated from the roots of A. membranaceus, covering 14 flavonoids, eight triterpenoid saponins and one phenylpropanoid. They were identified as 2'-methoxyisoliquiritigenin (1), echinatin (2), licochalcone B (3), 3',4',7-trihydroxyflavone (4), 4',7-dihydroxyflavone (5), 3',7,8-trihydroxy-4'-methoxyisoflavone (6), 4-hydroxycinnamic acid (7), calycosin (8), formononetin (9), 2',4,4'-trihydroxychalcone (10), pendulone (11), liquiritigenin (12), pratensein (13), calycosin-7-O-β-D-glucopyranoside (14), ononin (15), astragaloside IV (16), cyclocanthoside E (17), isoastragaloside II (18), astragaloside II (19), astragaloside III (20), isoastragaloside I (21), brachyoside B (22), and cycloaraloside A (23). Conclusion Compounds 1-7 are isolated from the plants of Astragalus Linn. for the first time.