[关键词]
[摘要]
目的 研究素心腊梅Chimonanthus praecox var.concolor种子中的化学成分。方法 采用柱色谱和重结晶法进行分离纯化并采用质谱、核磁共振等技术鉴定化学结构。结果 从素心腊梅种子95%乙醇提取物中分离鉴定了8个化合物,包括1个新化合物素心腊梅碱(1),1个新天然产物N1,N10-二甲基吲哚基乙胺(2)以及6个已知化合物:10-二十一碳烯酸(3)、β-谷甾醇(4)、β-胡萝卜苷(5)、胡萝卜苷亚油酸酯(6)、东莨菪素(7)和对羟基桂皮醛(8)。结论 化合物1 为新生物碱类化合物,命名为素心腊梅碱,2 为首次从天然界发现的化合物。其他所有化合物均为首次从该植物中得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents in the seeds of Chimonanthus praecox var. concolor. Methods The column chromatography and recrystallization methods were used for the isolation and the purification of compounds, and the spectroscopic methods (MS, NMR, etc.) were used for the structural identification. Results A new alkaloid chimonanthconin (1) and a new natural compound N1,N10-dimethyltryptamine (2), along with six known compounds, 10-heneicosenoic acid (3), β-sitosterol (4), β-daucosterol (5), daucoster linoleate (6), scopoletin (7), and p-hydorxyleinnamaldehyde (8), were isolated and identified. Conclusion Compound 1 is a new alkaloid and named chimonanthconin and compound 2 is a new natural compound. And other compounds are isolated from this plant for the first time.
[中图分类号]
[基金项目]