衰老以及衰老相关疾病使得人类生活的负担逐年加重。延缓衰老、减少衰老相关疾病的发生是解决问题的根源。动物模型是衰老研究的重要工具，就酵母、线虫、果蝇、斑马鱼、快速老化小鼠、D-半乳糖衰老模型、恒河猴等多种衰老研究中常用动物模型的特点及其在抗衰老药物筛选中的应用进展进行归纳总结，为衰老研究中相关动物模型的选择提供依据。

Aging and aging-related diseases make human life burden increase year by year. We can solve this problem by delaying aging and reducing the incidence of aging-related diseases. Animal model is an important tool for aging research, in this paper, we focused on all kinds of models for aging study including Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, Danio rerio, senescence accelerated mouse, D-galactose induced aging model, and rhesus. The characteristics, application status, and research progress of these models were introduced separately, which provides the basis for the selection of animal models in aging research.

国家自然科学基金资助项目（81673572）；山西省科技基础条件平台建设项目（2014091022）；山西省科技攻关项目（20140313008-14）；山西省应用基础研究项目（201601D021164）；山西省高校科技创新项目（2016120）