[关键词]
[摘要]
民族药玉簪Hosta plantaginea药用历史悠久,其全草、根、茎及花均可入药。玉簪花为蒙医药学传统常用药材,其单方及复方制剂均用于治疗咽喉肿痛等疾病,但其抗炎药效物质基础、作用机制及质量控制研究尚属于起步阶段。现代研究表明,玉簪具有抗炎镇痛、抗肿瘤、抗菌、抗病毒、抑制乙酰胆碱酯酶等药理活性,甾体类、生物碱类和黄酮类是其主要的化学成分。通过对玉簪植物的化学成分、药理活性、临床应用及质量控制进行系统的文献总结和分析,为该药材的合理用药及综合开发提供科学依据。
[Key word]
[Abstract]
The medicinal parts of Hosta plantaginea includes the whole plant,roots,stems,and flowers with a long history used as traditional folk herbal medicine.It has been commonly used for hundreds of years in Mongolia solely or in complex preparation for the treatment of sore throat and other diseases.However,there are few non-systemic studies on anti-inflammatory material basis,mechanisms,and quality control of H.plantaginea so far as well.The crude extracts or pure compounds from H.plantaginea showed anti-inflammatory,analgesic,cytotoxic,anti-microbial,anti-viral,anti-AchE activities,etc.In addition,previous phytochemical studies on H.plantaginea have indicated that steroids,alkaloids,and flavonoids are the major constituents in this plant.In this paper,we have systematically summarized and analyzed the chemical constituents,pharmacological activities,clinical application,and quality control of folk medicine H.plantaginea,which provides the foundation for the rational use and comprehensive development of H.plantaginea.
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[基金项目]
江西省“赣鄱英才555工程”人才引进计划项目(2012GPYC);国家自然科学基金项目(81503357);江西省自然科学基金项目(20161BAB215209);江西中医药大学人才引进项目(2014RC003)