[关键词]
[摘要]
目的 对烈香杜鹃Rhododendron anthopogonoides的化学成分进行研究。方法 采用Sephadex LH-20、MCI、硅胶柱色谱和制备液相色谱等手段进行分离纯化，利用理化性质及波谱数据鉴定化合物结构。结果 从烈香杜鹃醋酸乙酯部位分离出10个化合物，分别鉴定为咖啡酸（1）、反式阿魏酸（2）、山柰酚（3）、二氢槲皮素（4）、去甲丁香色原酮（5）、4-（3，4-二羟基苯基）-2-丁酮（6）、3，5-二羟基甲苯（7）、熊果酸（8）、3，4-二羟基苯甲酸乙酯（9）、procurcumenol（10）。结论 化合物1~3、5~7、9、10均为首次从烈香杜鹃中分离得到，化合物2、6、9、10为首次从杜鹃属植物中分离得到。
[Key word]
[Abstract]
Objective To study the chemical compositions of Rhododendron anthopogonoides.Methods The chemical constituents were isolated from R. anthopogonoides by Sephadex LH-20, MCI, silica gel column chromatography, and preparative-HPLC. The structures were assigned by physicochemical property and spectroscopic data.Results Ten compounds have been isolated from R. anthopogonoides and their structures were indentified as caffeic acid (1), trans-ferulic acid (2), kaempferol (3), dihydroquercetin (4), noreugenin (5), 4-(3,4-dihydroxyphenyl)-2-butanone (6), 3,5-dihydroxy toluene (7), ursolic acid (8), ethyl 3,4-dihydroxybenzoate (9), and procurcumenol (10).Conclusion Compounds 1—3, 5—7, 9, and 10 are obtained from R. anthopogonoides for the first time. Compounds 2, 6, 9, and 10 are obtained from the plants of Rhododendron L. for the first time.
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[基金项目]
青海省重大科技专项（2014-GX-A3A-01）
