目的 研究藏药蓝玉簪龙胆Gentiana veitchiorum地上部分中的黄酮苷类化学成分。方法 采用硅胶柱色谱、ODS中压柱色谱及制备高效液相色谱等方法对化合物进行分离纯化，通过1D和2D NMR方法鉴定化合物结构。结果 从蓝玉簪龙胆地上部分50%乙醇提取液中分离并鉴定了6个黄酮苷类化合物，分别为5,7,3',4'-四羟基黄酮-6-C-β-D-吡喃葡萄糖基-4'-O-β-D-吡喃葡萄糖基-（1→6）-β-D-吡喃葡萄糖苷（1）、异荭草素（2）、异牡荆苷（3）、异金雀花素（4）、异荭草素-4'-O-葡萄糖苷（5）和异皂草苷（6）。结论 化合物1为新化合物，命名为异荭草素-4'-二葡萄糖苷；化合物5和6为首次从该植物中分离得到。

Objective To study the flavonoid glycosides from the aerial parts of Gentiana veitchiorum. Methods The compounds were isolated and purified by silica gel and ODS chromatography in addition to p-HPLC. The structures of the isolated compounds were identified on the basis of 1D & 2D NMR spectroscopy methods. Results Six compounds were isolated from the aerial parts of G. veitchiorum and identified as 5, 7, 3', 4'-tetrahydroxyl flavone-6-C-β-D-glucopyranosyl-4'-O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside (1), isoorientin (2), isovitexin (3), isoscoparine (4), isoorientin-4'-O-glucoside (5), and isosaponarin (6). Conclusion Compound 1 is a new compound named isoorientin-4'-diglucoside, and compounds 5 and 6 are isolated from this plant for the first time.

西南民族大学中央高校基本科研业务费专项资金项目（2015NZYQN79）；西南民族大学研究生创新型科研项目（CX2016SZ048）