目的 研究苏木Caesalpinia sappan种子的化学成分。方法 采用柱色谱方法对苏木种子95%甲醇提取物进行分离纯化,结合波谱技术与化学方法进行结构鉴定。结果 从苏木种子95%甲醇提取物中分离得到了14个化合物,结构鉴定为phanginin F(1)、phanginin G(2)、phanginin H(3)、phanginin I(4)、phanginin J(5)、phanginin K(6)、phanginin L(7)、phanginin M(8)、柚皮素(9)、homoeriodictyol(10)、steraric acid(11)、1H-azirino[1,2-a] indole(12)、serlyticin A(13)、山柰酚(14)。结论 化合物9~14为首次从云实属植物中分离得到。

Objective To study the chemical constituents from the seeds of Caesalpinia sappan. Methods The constituents were isolated and purified by silica gel chromatograpy repeatedly from the seeds of C. sappan, and the structures were identified by spectral analysis and chemical methods. Results Fourteen compounds were isolated from the seeds of C. sappan and the structures were identified as phanginin F (1), phanginin G (2), phanginin H (3), phanginin I (4), phanginin J (5), phanginin K (6), phanginin L (7), phanginin M (8), naringenin (9), homoeriodictyol (10), steraric acid (11), 1H-azirino[1,2-a] indole (12), serlyticin A (13), and kaempferol (14). Conclusion Compounds 9-14 are obtained from the seeds of C. sappan and the plants of Caesalpinia Linn. for the first time.

国家自然科学基金资助项目(81502945);协和医学院青年基金(3332015141)