通过国内外文献调研显示,文冠果果壳中的化学成分主要有三萜、多酚(包括黄酮、酚酸、香豆素等)、甾醇、生物碱等。文冠果果壳的生物活性主要包括改善学习记忆功能、抗癌、抑制酪氨酸酶、治疗心脑血管疾病、抗氧化、抗炎和抑制胰脂肪酶活性等。其中文冠果壳苷(xanthoceraside)是文冠果果壳中量最高的三萜皂苷类成分,具有多种显著的生物活性。文冠果果壳作为文冠果榨油等使用的废弃物,具有进一步开发利用的药用价值。

To review the research progress in the chemical constituents from the husks of Xanthoceras sorbifolia and their biological activities for the first time. After a detailed investigation on the literatures at home and abroad, we had found that the primary chemical constituents from the husks of X. sorbifolia were triterpenoids and polyphenols (such as flavonoids, phenolic acids, coumarins etc), sterols, alkaloids, and so on. The biological activities of the chemical constituents from the husks of X. sorbifolia showed mainly as improving the ability of learning and memory, anticancer effects, inhibition on tyrosinase, curing cardiovascular and cerebrovascular diseases, anti-oxidant and anti-inflammatory effects, and inhibiting pancreatic lipase activity. Xanthoceraside is a primary triterpenoid saponin purified from the husks of X. sorbifolia, with highest content and a variety of biological activities. The husks as the waste of the oil-extracting from X. sorbifolia, this paper provides the references for further understanding and utilization of the medicinal values in the husks of X. sorbifolia.

甘肃省博士后科研项目择优资助