目的 研究列当Orobanche coerulescens全草的化学成分。方法 采用大孔树脂、硅胶和反相ODS柱色谱进行分离和纯化,通过HR-ESI-MS、NMR、2D-NMR等波谱数据确定化合物的结构。结果 从列当全草50%乙醇提取物中提取分离得到1个新苯乙醇苷,鉴定为2-(3-甲氧基-4-羟基)-苯基-乙醇-1-O-α-L-[(1→3)-4-O-乙酰基-鼠李糖基-4-O-阿魏酰基]-O-β-D-葡萄糖苷。结论 化合物1为新化合物,命名为列当苷A。

Objective To study the chemical constituents from the whole plant of Orobanche coerulescens. Methods The constituents were isolated and purified by using various column chromatographic techniques including D₁₀₁, silica gel, and ODS, and the structures were identified by spectroscopic analyses including HR-ESI-MS, NMR, and 2D-NMR. Results A new phenethyl alcohol glycoside was isolated from 50% ethanol extract in the whole plant of O. coerulescens, and its structure was identified as 2-(3-methoxy-4-hydroxy)-phenyl-ethanol-1-O-α-L-[(1→3)-4-O-acetyl-rhamnopyranosyl-4-O-feruloyl]-O-β-D-glucopyranoside. Conclusion Compound 1 is a new compound named as orobancheoside A.