角茴香为罂粟科角茴香属植物,是民族药和地方习用药材,以藏药最为常用,具清热、解毒、镇痛之功效,治疗"赤巴"等多种热症、瘟疫及瘟毒。角茴香及其同属植物主要有效成分为异喹啉类生物碱,角茴香属植物有抑菌、保肝、镇痛抗炎、抗病毒等作用。针对角茴香属植物的资源分布、化学成分及药理活性进行了归纳总结,为该属植物的进一步研究及开发提供参考。

Hypecoi Erecti Herba is one of ethnic and folk medicines in China, mostly known in Tibetan medicine. It has the function of heat-clearing and detoxifying, and analgesia, indicated for the treatment of a variety of heat syndrome, such as "Chi Ba" pestilence, and warm toxin. Previous phytochemical studies revealed isoquinoline alkaloids are its main chemical components, and contemporary pharmacological research demonstrated that Hypecoi Erecti Herba has antibacterial, liver protection, analgesic, anti-inflammatory, and antiviral activities. The present paper describes the resource distribution, chemical constituents, and pharmacological activities of the plants in Hypecoum L. to provide the references for further research and development of the plants in Hypecoum L.

国家自然科学基金资助项目(81303309,81473426)