紫葳科(Bignoniaceae)角蒿属Incarvillea Juss. 为一年或多年生草本植物,分布自中亚经喜马拉雅山区至东亚等地区,全世界约有15种,我国产11种。该属多种植物具有悠久的民间药用历史,用于治疗胃痛、肝炎、月经不调等症。化学成分主要有单萜生物碱、环己乙醇、环烯醚萜及苯丙素类等,具有镇痛、抗氧化和抗炎等活性。对角蒿属植物化学成分及药理活性研究进行了系统概述,为该属植物的深入研究与开发利用提供参考。

The genus Incarvillea Juss. (Bignoniaceae) consists of about fifteen species distributed in the regions stretching from Central to East Asia along Himalaya Mountains, including eleven species in China. The plants of Incarvillea Juss. are annual or perennial herbs with attractive flowers, most of which are used as traditional folklore medicines for the treatments of stomachache, hepatitis, and abnormal menstruation. Phytochemical studies on the plants in Incarvillea Juss. have disclosed the presence of monoterpene alkaloids, cyclohexyl-ethanol, iridoids, phenylpropanoid, etc. Pharmacological activities include analgesic, anti-oxidant, and anti- inflammatory activities. In this review, the chemical constituents and their biological activities of medicinal plants from Incarvillea Juss. are comprehensively discussed.

“重大新药创制”科技重大专项“十二五”计划(综合性新药研究开发技术大平台,2012ZX09301-002-001-026);药植所创新团队发展计划资助项目;湖南省科技计划项目(2012FJ4293);湖南省高校产业化培育项目项目(11CY013)