目的 制备芦丁-Cu²⁺配合物印迹聚合物,验证其吸附性能。方法 功能单体为α-甲基丙烯酸,在极性环境中制备芦丁-Cu²⁺配位分子印迹聚合物;采用紫外光谱和红外光谱研究聚合物结构及制备机制;以平衡吸附试验及对芦丁类似物的吸附试验研究聚合物的特异性吸附能力。结果 制备的聚合物与芦丁-Cu²⁺配位分子通过配位键及分子间作用力结合,具有明显的特异性吸附作用。结论 制备的芦丁-Cu²⁺配位分子印迹聚合物对芦丁-Cu²⁺配位分子具有特异性识别作用,可用于中药有效成分芦丁的分离和富集。

Objective To prepare rutin-Cu²⁺ complex imprinted polymer and study its adsorption ability. Methods The polymer was prepared in mixed poler solvent, using α-methacrylic acid as functional monomer. The structure and preparation mechanism were studied by UV-vis spectroscopy and IR spectroscopy. Results The polymer and rutin-Cu²⁺ complex were combined by coordinate bond and intermolecular force, the polymer had remarkably specific adsorption to complex of rutin-Cu²⁺. Conclusion Rutin-Cu²⁺ complex molecularly imprinted polymer has great adsorption and specific identification to rutin-Cu²⁺, and can be used in extraction and separation of Chinese medicine effective constituent rutin.

山东省科学技术发展计划项目(2013YD19004)