目的 建立何首乌药材Polygoni Multiflori Radix中无机元素的电感耦合等离子体质谱(ICP-MS)分析方法, 并对不同产地何首乌及商品药材中无机元素进行分析比较。方法 样品经微波消解后, 采用ICP-MS法测定无机元素的量, 并用SPSS 16.0对数据进行相关性分析、主成分分析。结果 检测了何首乌药材中24种元素, 元素之间有一定的相关性, K、Fe、Mg、Ca、P的量较高, 重金属及有害元素的量应引起关注;主成分分析选出6个主因子, 得出Fe、Si、Ca、Al、K、Be、Sb、Mn、Zn、Ba是何首乌的特征无机元素。结论 为何首乌药材的质量控制及安全性评价提供依据。

Objective To establish a method for simultaneous analysis on the inorganic elements in Polygoni Multiflori Radix. by inductively coupled plasma mass spectrometry (ICP-MS) and compare the inorganic elements in Polygoni Multiflori Radix between different origin and commercial herbs. Methods The sample solutions were analyzed by ICP-MS after microwave digestion. The data of correlations, principal components, and cluster were analyzed with the SPSS 16.0 software. Results Twenty four inorganic elements in Polygoni Multiflori Radix were determined. And there were some correlations among the inorganic elements in Polygoni Multiflori Radix. The contents of K, Fe, Mg, Ca, and P were abundant. The content of heavy metals and harmful elements should be caused for concern. Six main factors were selected by principal component analysis (PCA). The PCA results showed that Fe, Si, Ca, Al, K, Be, Sb, Mn, Zn, and Ba may be the characteristic elements in Polygoni Multiflori Radix. Conclusion This experiment provides the evidence for the quality control and safety evaluation of Polygoni Multiflori Radix.

国家科技支撑计划项目(2011BAI13B04);江苏高校优势学科建设工程资助项目(ysxk-2014)