[关键词]
[摘要]
目的 研究野生白木香Aquilaria sinensis叶的化学成分。方法 采用硅胶柱色谱等方法进行分离纯化，根据理化性质和波谱解析鉴定化合物结构。结果 从野生白木香叶70%丙酮渗漉提取物中分离得到13个化合物，分别鉴定为反-6-十八烯酸（1）、亚油酸乙酯（2）、洋芹素-7, 4’-二甲醚（3）、4-氰基苯甲醛（4）、木犀草素-7, 3’, 4’-三甲醚（5）、芫花素（6）、对苯二甲酸二 (4-辛) 酯（7）、6-羟基-7, 4’-二甲氧基黄酮（8）、5-羟基-7, 2’, 4’, 5’-四甲氧基黄酮（9）、5, 4’-二羟基-7, 3’-二甲氧基黄酮（10）、槲皮素（11）、山柰酚（12）、对羟基苯甲酸（13）。结论 化合物4、8、9为首次从瑞香科植物中分离得到。
[Key word]
[Abstract]
Objective To investigate the chemical constituents from the leaves of wild Aquilaria sinensis. Methods The powder of the dried leaves was percolated with 70% acetone. Various chromatographic methods were employed to isolate the compounds and their structures were established by spectroscopic analysis. Results Thirteen compounds were isolated and identified as 6-E-octadecenoic acid (1), ethyl linoleate (2), apiolin-7, 4'-dimethyl ether (3), 4-cyanobenzaldehyde (4), luteolin-7, 3', 4'-trimethyl ether (5), genkwanin (6), p-phthalic acid di (4-octyl) ester (7), 6-hydroxy-7, 4'-dimethoxyflavone (8), 5-hydroxy-7, 2', 4', 5'- tetramethoxyflavone (9), 5, 4'-dihydroxy-7, 3'-dimethoxyflavone (10), quercetin (11), kaempferol (12), and 4-hydroxybenzoic acid (13). Conclusion Thirteen compounds have been identified from wild A. sinensis leaves. Compounds 4, 8, and 9 are firstly isolated from the plants of Thymelaeaceae.
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[基金项目]
国家自然科学基金资助项目（81172982）；广东省科技计划项目（2010A030100006）；中山市科技计划项目（20101H006，20123A276）
