目的 建立薏苡仁油的融合指纹图谱。方法 薏苡仁油经气相色谱-质谱联用（GC-MS）和高效液相色谱-蒸发光散射（HPLC-ELSD）检测，2种分析方法所得数据进行峰面积标准化处理，运用中药色谱指纹图谱相似度评价软件进行指纹图谱融合。结果 薏苡仁融合指纹谱获得21个共有峰，GC-MS技术鉴定出13种脂肪酸酯类成分；HPLC-ELSD法检测部分得到8个共有峰。结论 融合指纹图谱的整体性好，信息量大，结合质谱技术部分消除了单一测定方法指纹图谱的模糊性，为中药质量控制研究提供了一定的参考。

Objective To establish the fusion-fingerprint of Coicis Semen oil. Methods The Coicis Semen oil was analyzed by GC-MS and HPLC-ELSD, and the fusion-fingerprint was originated from the Computer Aided Similarity Evaluation software based on the normalized data acquired by the above two methods. Results Twenty-one common peaks existed in the fusion-fingerprint of which there were 13 kinds of aliphatic esters detected by GC-MS and 8 kinds of triglyceride ingredients detected by HPLC-ELSD. Conclusion The fusion-fingerprint established on GC-MS combined with HPLC-ELSD could provide integrity and more information for the quality control of Chinese materia medica.

国家重点基础研究发展计划“973”课题（2013CB531803）