目的 研究宽苞水柏枝Myricaria bracteata的化学成分。方法 应用多种色谱技术进行分离纯化，根据化合物的理化性质和波谱数据鉴定化合物的结构。结果 从宽苞水柏枝嫩枝95%乙醇提取物的醋酸乙酯萃取部位和大孔树脂30%乙醇洗脱部分中分离得到14个化合物，分别鉴定为丁香脂素（1）、(?)-南烛木脂酚（2）、(?)-异落叶松脂素（3）、Ν-反式阿魏酰基酪胺（4）、Ν-反式阿魏酰基-3-甲氧基酪胺（5）、Ν-反式阿魏酰基-2′-甲氧基酪胺（6）、山柰酚-3-O-β-D-吡喃葡萄糖醛酸-6″-甲酯（7）、槲皮素-3-O-β-D-吡喃葡萄糖醛酸-6″-甲酯（8）、槲皮苷（9）、鼠李柠檬素（10）、没食子酸（11）、没食子酸甲酯（12）、E-咖啡酸（13）、E-阿魏酸（14）。结论 化合物1～6、14为首次从该属植物中分离得到，化合物7、8、12、13为首次从该植物中分离得到。

Objective To investigate the chemical constituents from the twigs of Myricaria bracteata. Methods The chemical constituents were isolated and purified by column chromatography. Their structures were identified on the basis of spectroscopic data, such as NMR, MS, and physicochemical properties. Results Fourteen compounds were isolated from M. bracteata and identified as syringaresinol (1), (?)-lyoniresinol (2), (?)-isolariciresinol (3), N-trans-feruloyltyramine (4), N-trans-feruloyl-3-methoxytyramine (5), N-trans-feruloyl-2′-methoxytyramine (6), kaempferol-3-O-β-D-glucuronic acid methylester (7), quercetin-3-O-β-D-glucuronic acid methylester (8), quercitrin (9), rhamnocitrin (10), gallic acid (11), gallicin (12), E-caffeic acid (13), and E-ferulic acid (14). Conclusion Compounds 1—6 and 14 are isolated from the plants of this genus for the first time. Compounds 7, 8, 12, and 13 are isolated from the twigs of M. bracteata for the first time.

国家自然科学基金资助项目（21072233）