目的 研究栀子Gardenia jasminoides的干燥成熟果实中单萜类化学成分。方法 采用多种柱色谱方法分离纯化，通过理化常数测定和光谱分析鉴定化合物的结构。结果 从栀子果实80%乙醇提取物中分离得到了12个单萜类化合物，分别鉴定为jasminoside B（1）、jasminoside G（2）、jasminodiol（3）、(7R)-6-羟甲基-1, 1, 5-三甲基环己-3-烯酮（4）、(7S)-6-羟甲基-1, 1, 5-三甲基环己-3-烯酮（5）、bornyl-6-O-β-D-xylopyranosyl-β-D-glucopyranoside（6）、(10R, 11R)-栀子二醇（7）、(10S, 11S)-栀子二醇（8）、(5S, 9S)-gardenate A（9）、(5R, 9R)-gardenate A（10）、jasminoside E（11）、5, 6-二羟甲基-1, 1-二甲基环己-4-烯酮（12）。结论 化合物5、6、8、10和12为首次从栀子中分离得到。

Objective To investigate the chemical constituents of monoterpenes in the fruits of Gardenia jasminoides. Methods Various column chromatographies were used in the isolation and purification, and the physicochemical constant determination and spectral analysis were adopted to identify the chemical structures of monoterpenes. Results Twelve monoterpenes were isolated from G. jasminoides, such as jasminoside B (1), jasminoside G (2), jasminodiol (3), crocusatin-C (4), (7S)-6-(hydroxymethyl)-1, 1, 5- trimethylcyclohex-3-enone (5), bornyl-6-O-β-D-xylopyranosyl-β-D-glucopyranoside (6), (10R, 11R)-gardendiol (7), (10S, 11S)- gardendiol (8), (5S, 9S)-gardenate A (9), (5R, 9R)-gardenate A (10), jasminoside E (11), and 5, 6-dihydroxymethyl-1, 1- dimethylcyclohex-4-enone (12). Conclusion Compounds 5, 6, 8, 10, and 12 are first isolated from this plant.

国家科技部“十二五”科技支撑计划课题（2011BAI04B01）；“道地药材及特色中药资源栀子研究”校级专项课题（ZX1021）