目的 研究黄荆Vitex negundo的化学成分。方法 采用十八烷基硅烷键合硅胶（ODS）、葡聚糖凝胶Sephadex LH-20和硅胶柱色谱等色谱技术，对黄荆的化学成分进行分离纯化，通过波谱数据分析，鉴定了化合物的结构。结果 从黄荆95%乙醇提取物正丁醇萃取部位分离得到11个化合物，分别鉴定为异荭草素（1）、黄荆诺苷（2）、木犀草素7-O-β-D-吡喃葡萄糖苷（3）、异牡荆苷（4）、木犀草素3′-O-β-D-吡喃葡萄糖醛酸苷（5）、芹菜素7-O-β-D-葡萄糖苷（6）、山柰酚3-O-β-D-吡喃葡萄糖苷（7）、迷迭香酸甲酯（8）、5-O-咖啡酰基-奎宁酸甲酯（9）、咖啡酸（10）及银桦苷G（11）。结论 化合物5～11为首次从牡荆属植物中分离得到，化合物3、4为首次从该植物中分离得到。

Objective To investigate the chemical constituents from Vitex negundo. Methods The chemical constituents were separated and purified by column chromatography including ODS, Sephadex LH-20, and silica gel columns. Their structures were elucidated on the basis of physicochemical properties and spectral data. Results Eleven compounds were identified as isoorientin (1), vitegnoside (2), luteolin-7-O-β-D-glucopyranoside (3), isovitexin (4), luetolin-3′-O-β-D-glucuronide (5), apigenin-7-O-β-D-glucoside (6), kaempferol-3-O-β-D-glucopyranoside (7), methyl rosmarinate (8), 5-O-caffeoyl quinic acid methylester (9), caffeic acid (10), and grevilloside G (11), respectively. Conclusion Compounds 3 and 4 are isolated from V. negundo for the first time, and compounds 5—11 are firstly obtained from the plants of Vitex Linn.