目的 建立强肝胶囊HPLC指纹图谱并对其进行化学模式识别。方法 采用Diamonsil C₁₈柱（250 mm×4.6 mm，5 μm），在230 nm波长下，以乙腈-0.05%磷酸水溶液进行梯度洗脱，测定了44批强肝胶囊样品；应用相似度分析软件建立强肝胶囊指纹图谱的共有模式，并对色谱峰进行了指认。结果 建立强肝胶囊HPLC指纹图谱，在确定的方法下，得到44批强肝胶囊的色谱图，并获得了44批样品的相似度；确定共有峰14个，其中13个归属到各药材，11个已确认成分。结论 强肝胶囊的HPLC指纹图谱的构建和共有色谱峰成分的确定为强肝胶囊药品质量控制提供参考。

Objective To establish HPLC fingerprint for Qianggan Capsule and identify the chemical pattern recognition. Methods The HPLC method was used with Diamonsil-C₁₈ column (250 mm × 4.6 mm, 5 μm), under the 230 nm detection wavelength, gradient eluted by acetonitrile-0.05% H₃PO₄. The common mode of HPLC fingerprint for 44 batches of Qianggan Capsule was established with similarity analyses and the peaks were identified. Results Under the selected spectrum condition, the HPLC fingerprint for 44 batches of Qianggan Capsule and similarities for 44 batches of samples were obtained. Fourteen peaks were found, 13 belong to herbs and 11 were assigned. Conclusion The establishment of HPLC fingerprint of Qianggan Capsule and the identification of peaks provide more reference for the quality control of Qianggan Capsule.