目的研究我国特有植物青钱柳Cyclocarya paliurus的化学成分。方法利用硅胶和葡聚糖凝胶等色谱技术进行分离纯化，根据NMR、MS等波谱方法和理化性质鉴定化合物的结构。结果从青钱柳叶具有调血脂活性部位中分离和鉴定了12个化合物，分别为pterocaryoside B(1)、青钱柳酸B(2)、2α-羟基乌苏酸(3)、arjunolic acid(4)、乌苏酸(5)、齐墩果酸(6)、蒲公英萜醇(7)、6，9-dihydroxy-7-megastigmen-3-one(8)、loliolide(9)、山柰酚-3-O-α-L-鼠李糖苷(10)、山俞酸甘油单酯(11)、β-谷甾醇(12)。结论化合物7～10为首次从该属植物中分离得到。

ObjectiveTo study the chemical constituents isolated from the leaves of Cyclocarya paliurus. MethodsThe chemical constituents from the leaves of C. paliuruswere isolated and purified by chromatographyon silica gel and Sephadex LH-20 columns. Their structures were identified on the basis of spectroscopic data and physicochemical properties. Results Twelve compounds were isolated and identified as pterocaryoside B (1), cyclocaric acid B (2), 2α-hydroxyursolic acid (3), arjunolic acid (4), ursolic acid (5), oleanolic acid (6), taraxerol (7), 6, 9-dihydroxy-7-megastigmen-3-one (8), loliolide (9), kaempferol-3-O-α-L-hamnopyranoside (10), behenic acid 1-propanetriol ester (11), and β-sitosterol (12). ConclusionCompounds 7—10are isolated from the plants in Cyclocarya Iljinskaja for the first time.

国家科技重大专项“面向新药发现的数字化中药化学成分库”（2011ZX09307-002-01）