目的 研究飞机草Eupatorium odoratum地上部分的化学成分。方法 利用正相硅胶、MCI柱、反相RP-18柱色谱及葡聚糖凝胶Sephadex LH-20等手段进行分离纯化,根据波谱数据鉴定化合物的结构。结果 分离鉴定了20个化合物,分别为飞机草素(1)、山柰酚(2)、山柰酚-4′-甲基醚(3)、槲皮素(4)、五桠果素(5)、异鼠李素(6)、木犀草素-4′-甲基醚(7)、3,4′-二羟基-5,6,7-三甲氧基黄酮(8)、野黄芩素四甲醚(9)、金合欢素(10)、异樱花素(11)、4′-羟基-5,6,7-三甲氧基黄烷酮(12)、5,6,7,4′-四甲氧基黄烷酮(13)、二氢山柰素(14)、香橙素-7,4′-二甲醚(15)、柚皮素-7,4′-二甲醚(16)、5,6,7-三羟基-4′-甲氧基黄烷酮(17)、5,6,7,3′,4′-五甲氧基黄烷酮(18)、正十六碳酸α-甘油酯(19)、β-谷甾醇(20)。结论 化合物6～9、16～19均为首次从该植物中分离得到。

Objective To study the chemical constituents in the aerial parts of Eupatorium odoratum.Methods The compounds were isolated and repeatedly purified by chromatography on silica gel,MCI,RP-18,and Sephadex LH-20 columns,and their structures were elucidated on the basis of spectral analyses.Results Twenty compounds were obtained and identified as odoratin (1),kaempferol (2),kaempferol-4′-methyl ether (3),quercetin (4),dillenetin (5),isorhamnetin (6),luteolin-4′-methyl ether (7),3,4′-dihydroxy-5,6,7-trimethoxyflavone (8),scutellaretin tetramethyl ether (9),acacetin (10),isosakuranetin (11),4′-hydroxy-5,6,7-trimethoxyflavanone(12),5,6,7,4′-tetramethoxyflavanone (13),dihydrokaempferide (14),aromadendrin-7,4′-dimethyl ether (15),naringenin-7,4′-dimethyl ether (16),5,6,7-trihydroxy-4′-methoxyflavanone (17),5,6,7,3′,4′-pentamethoxyflavanone (18),1-glycerolhexadecylate (19),and β-sitosterol (20),respectively.Conclusion Compounds 6-9 and 16-19 are obtained from the plant for the first time.

国家自然科学基金资助项目“有害入侵植物飞机草的进化”(30830027)