目的 对云贵腺药珍珠菜Lysimachia stenosepala var. flavescens的化学成分进行研究。方法 运用硅胶柱、凝胶柱、中压柱、聚酰胺柱等色谱技术进行分离纯化，根据波谱数据进行结构鉴定。结果 从云贵腺药珍珠菜乙醇提取物中分离得到12个化合物，分别鉴定为山柰酚（1）、槲皮素（2）、鼠李柠檬素（3）、山柰酚-3-O-β-D-葡萄糖苷（4）、槲皮素-3-O-β-D-葡萄糖苷（5）、山柰酚-3-O-α-L-鼠李糖苷-(1→2)-β-D-葡萄糖苷（6）、山柰酚-3-O-α-L-鼠李糖苷-(1→6)-β-D-葡萄糖苷（7）、槲皮素-3-O-β-D-木糖苷-(1→2)-O-β-D-葡萄糖苷（8）、山柰酚-3-O-(2-O-α-L-鼠李糖苷-6-O-β-D-木糖苷)-β-D-葡萄糖苷（9）、β-谷甾醇（10）、原报春花素A（11）、β-胡萝卜苷（12）。结论 化合物1～12为首次从该植物中分离得到，其中化合物8、9为首次从珍珠菜属中分离得到。

Objective To investigate the chemical constituents in Lysimachia stenosepala var. flavescens. Methods Compounds were isolated by chromatography on silica gel, Sephadex LH-20, and polyamide columns and their structures were identified by spectral data. Results Twelve compounds were identified as kaempferol (1), quercetin (2), rhamnocitrin (3), kaempferol-3-O-β-D-glucopyranoside (4), quercetin-3-O-β-D-glucopyranoside (5), kaempferol-3-O-α-L-rhamnopyranosyl-(1→2)-β-D- glucopyranoside (6), kaempferol-3-O-α-L- rhamnopyranosyl-(1→6)-β-D-glucopyranoside (7), quercetin-3-O-β-D-xylopyranosyl-(1→2)- O-β-D-glucopyranoside (8), kaempferol-3-O-(2-O-α-L-rhamnopyranosyl-6-O-β-D-xylopyranosyl)-β-D-glucopyranoside (9), β-sitosterol (10), protoprimulagenin A (11), and β-daucosterol (12). Conclusion Compounds 1—12 are isolated from this plant for the first time and compounds 8 and 9 are isolated from the plants in Lysimachia L. for the first time.