目的 研究大接骨丹Torricellia angulata var. intermedia根皮的化学成分。方法 采用硅胶、大孔树脂、Sephadex LH-20和ODS等色谱手段进行化学成分的分离纯化；依据理化性质、波谱数据和相关文献进行结构鉴定。结果 分离鉴定了10个化合物，分别鉴定为丁香树脂酚（1）、豆甾醇（2）、3,4,5,7-四羟基-苯乙酸（3）、豆甾-5,11-二烯-3β-醇（4）、22,23-二氢豆甾醇（5）、β-胡萝卜苷（6）、26,27-dinor-4,4-dimethyl-cholesta-8,14-dien-3-ol（7）、硬脂酸（8）、软脂酸（9）、4-羟基-3,5-二甲氧基苯甲醛（10）。结论 其中化合物3为新的天然产物，化合物1、2、4、5、7、10为首次从该植物中分离得到。

Objective To investigate the chemical constituents in the root bark of Torricellia angulata var. intermedia. Methods The compounds were isolated by means of column chromatography on silica gel, macroporous resin, Sephadex LH-20, and ODS, and their structures were elucidated by physicochemical properties and spectra. Results Ten compounds were obtained and identified as syringaresinol (1), stigmasterol (2), 3,4,5,7-tetrahydroxy benzeneacetic acid (3), stigmasta-5,11-dien-3β-ol (4), 22,23-dihydrostigmasterol (5), β-daucosterol (6), 26,27-dinor-4,4-dimethyl-cholesta-8,14-dien-3-ol (7), octadecanoic acid (8), palmitic acid (9), and 4-hydroxy-3,5-dimethoxyl benzaldehyde (10). Conclusion Compound 3 is isolated from natural plant for the first time and compounds 1, 2, 4, 5, 7, and 10 are isolated from this plant for the first time.

国家自然科学基金资助项目（30973865）；教育部新世纪优秀人才支持计划（NCET-08-0224）