目的研究细皱香薷Elsholtzia rugulosa叶的化学成分。方法采用柱色谱法进行分离和纯化,通过波谱分析鉴定结构。结果从乙醇提取物中分离得到了12个化合物,鉴定结构分别为洋芹素-7-O-β-D-葡萄糖苷(Ⅰ)、木犀草素-7-O-β-D-葡萄糖苷(Ⅱ)、刺槐素-7-O-β-D-葡萄糖苷(Ⅲ)、木犀草素-7-O-(6″-乙酰基)-β-D-葡萄糖苷(Ⅳ)、苯甲醇-β-D-葡萄糖苷(Ⅴ)、prunasin(Ⅵ)、β-谷甾醇(Ⅶ)、桦木酸(Ⅷ)、2α-羟基乌苏酸(Ⅸ)、2α-羟基齐墩果酸(Ⅹ)、洋芹素(Ⅺ)和木犀草素(ⅩⅡ)。结论化合物Ⅰ、Ⅲ、Ⅳ、Ⅸ和Ⅹ为首次从该种植物中分离得到。

Objective To study the chemical constituents from the leaves of Elsholtzia rugulosa.Methods Compounds were isolated and purified by silica gel column and Sephadex LH-20 chromatography.Their chemical structures were identified by spectral data.Results Twelve compounds were isolated,purified,and identified as:apigenin-7-O-β-D-glucopyranoside (Ⅰ),luteolin-7-O-β-D-glucopyranoside (Ⅱ),acacetin-7-O-β-D-glucopyranoside (Ⅲ),luteolin-7-O-(6″-acetyl)-β-D-glucopyranoside (Ⅳ),benzyl alcohol-β-D-glucopyranoside (Ⅴ),prunasin (Ⅵ),β-sitosterol (Ⅶ),betulinic acid (Ⅷ),corosolic acid (Ⅸ),maslinic acid (Ⅹ),apigenin (Ⅺ) and luteolin (ⅩⅡ).Conclusion Compounds Ⅰ,Ⅲ,Ⅳ,Ⅸ,and Ⅹ are obtained from this plant for the first time.