目的 研究傣药芽鲁哈咪卖Rhinacanthus nasutus 的化学成分。方法 用色谱方法分离成分,根据理化性质和光谱分析鉴定结构。结果 分离得到9个化合物和2个混合物,鉴定为C₂₆-C₃₂烷混合物(Ⅰ)、α-软脂酸单甘油酯(Ⅱ)、软脂酸(Ⅲ)、硬脂酸(Ⅳ)、木焦油酸(Ⅴ)、β-谷甾醇(Ⅵ)、羽扇豆醇(Ⅶ)、对羟基苯甲酸(Ⅷ)、胡萝卜苷(Ⅸ)、α-乙基-D-吡喃艾杜糖苷(Ⅹ)、硝酸钾与硝酸钠混合物(Ⅺ)。结论 化合物Ⅹ是分离过程产生的人工新化合物,化合物Ⅰ-Ⅴ、Ⅷ-Ⅺ是首次从傣药芽鲁哈咪卖中分得。

Objective To study the chemical constituents of the Dai ethno-medicine Rhinacanthus nasutus.Methods The chemical constituents had been spearated with chromatography and their structures were determined by spectral analyses.Results Nine compounds and two mixture were isolated and identified as C₂₆-C₃₂ alkyl mixture(Ⅰ),α-monopalmitin(Ⅱ),palmitic acid(Ⅲ),stearic acid(Ⅳ),lignoceric acid(Ⅴ),β-sitosterol(Ⅵ),lupeol(Ⅶ),p-hydroxy benzoic acid(Ⅷ),daucosterol(Ⅸ),α-ethyl-D-idosopyranoside(Ⅹ),and mixture of KNO₃ and NaNO₃(Ⅺ).Conclusion Compound Ⅹ is a new artificial compound during isolation and compounds Ⅰ-Ⅴ,Ⅷ-Ⅺ are isolated from R. nasutus for the first time.

云南省教育厅科学研究基金项目(5E0463C)