目的 研究远志科远志属植物黄花倒水莲Polygala fallax 根的化学成分。方法 采用硅胶柱色谱、Sephadex L H-20柱色谱以及重结晶等方法,分离纯化黄花倒水莲的化学成分,通过波谱方法对结构进行解析和鉴定。结果 确定了6个化合物的结构,分别为3-O-β-D-glucopyranosyl senegenic acid(Ⅰ)、远志皂苷(tenuifolin,Ⅱ)、细叶远志皂苷元(presenegenin,Ⅲ)、1,7-二甲氧基-2,3-亚甲二氧基酮(1,7-dimethoxy-2,3-methylenedioxy xanthone,Ⅳ)、芥子酸(sinapinic acid,Ⅴ)、阿魏酸(ferulic acid,Ⅵ)。结论 化合物Ⅲ-Ⅵ为首次从该种植物中分离得到,化合物Ⅰ为首次从该植物中发现的远志酸型皂苷,且为新化合物,命名为黄花倒水莲皂苷A(fallaxsaponinA)。

Objective To investigate the chemical constituents of Polygala fallax.Methods The chemical constituents were isolated and purified via silica gel and Sephadex L H-20 column chromatography as well as recrystallization.Their structures were determined on the basis of spectral analysis and physicochemical properties.Results Six compounds were isolated and identified as 3-O-β-D-glucopyranosyl senegenic acid(Ⅰ),tenuifolin(Ⅱ),presenegenin(Ⅲ),1,7-dimethoxy-2,3-methylenedioxy xanthone(Ⅳ),sinapinic acid(Ⅴ),ferulic acid(Ⅵ).Conclusion Compounds Ⅲ-Ⅵ are isolated from P. fallax for the first time.Compound Ⅰ is a new triterpenoid saponin,named fallaxsaponin A.