目的研究酸浆Physalis alkekengi var.franchetii的活性成分。方法酸浆的宿萼经乙醇渗漉提取,提取物经硅胶、Sephadex LH-20色谱分离,并通过理化常数和波谱学方法鉴定化合物结构。结果分离鉴定了个化合物,分别为β-谷甾醇(Ⅰ)、酸浆苦素A(Ⅱ)、酸浆苦素B(Ⅲ)、酸浆苦素O(Ⅳ)、酸浆苦素L(Ⅴ)、酸浆苦素M(Ⅵ)、胡萝卜苷(Ⅶ)、商陆素(Ⅷ)、5,4',5'-三羟基-7,3'-二甲氧基黄酮醇(Ⅸ)、木犀草素(Ⅹ)、木犀草素-7-O-β-D-葡萄糖苷(Ⅺ)。结论化合物Ⅸ为新化合物,命名为酸浆黄酮醇(physaflavonol)。

Objective To study the active constituents of Physalis alkekengi var. franchetii MethodsThe compounds were separated by silica gel and Sephadex LH-20 chromatography method, their structures were identified on the spectral analyses and physical data. Results Eleven compounds were isolated and identified as β-sitosterol (Ⅰ), physalin A (Ⅱ), physalin B (Ⅲ), physalin O (Ⅳ), physalin L (Ⅴ), physalin M (Ⅵ), daucosterol (Ⅶ), ombuine (Ⅷ), 5, 4', 5'-trihydroxy-7, 3'-dimethoxy-flavonol (Ⅸ), luteolin (Ⅹ), and luteolin-7-O-β-D-glucopyranoside (Ⅺ). Conclusion Compound Ⅸ is a new compound named physaflavonol.

科技部基础平台项目(2005DKA2004)