目的 建立川芎挥发油特征指纹图谱,以科学评价和有效地控制川芎药材内在质量。方法 采用GC-MS法分析10批川芎挥发油化学成分,标定共有峰和确定特征指纹峰。结果 鉴定出13个共有峰,确定其中8个共有峰为其特征指纹峰。以特征指纹峰作为评价指标,方法的精密度、稳定性、重现性良好。结论 采用GC-MS法建立川芎挥发油特征指纹图谱,其特征性和专属性强,可作为川芎药材质量控制的有效手段。

Objective To establish characteristic fingerprint of essential oil in Rhizoma Chuanxiong and to scientifically evaluate and effectively control the inner quality of Rhizoma Chuanxiong.Methods Chemical components in essential oil from ten batches of Rhizoma Chuanxiong samples were analyzed by GC-MS method and the common peaks and characteristic peaks were identified.Results Thirteen common peaks were identified and eight characteristic peaks was established.Precision,stability and reproducibility tests had good results with the characteristic peaks as indexes.Conclusion The established characteristic fingerprint is very exclusive and can be used for the quality control of Rhizoma Chuanxiong.