目的对狗肝菜Dicliptera chinensis全草的化学成分进行研究。方法采用硅胶柱色谱和制备性薄层色谱进行分离、纯化,IR、NMR和MS等方法进行结构鉴定。结果从环己烷萃取部分得到13个化合物,分别鉴定为正三十六烷醇(Ⅰ)、硬脂酸(Ⅱ)、羽扇烯酮(Ⅲ)、羽扇豆醇(Ⅳ)、谷甾烷-4-烯-3-酮(Ⅴ)、豆甾烷-5-烯-7-酮-3β-棕榈酸酯(Ⅵ)、β-谷甾醇(Ⅶ)、齐墩果酸(Ⅷ)、3β,6β-豆甾烷-4-烯-3,6-二醇(Ⅸ)、6β-羟基-豆甾烷-4-烯-3-酮(Ⅹ)、3β-羟基-豆甾烷-5-烯-7-酮(Ⅺ)、去氢催叶萝芙叶醇(Ⅻ)和催叶萝芙叶醇(ⅩⅢ)。结论除Ⅱ化合物和Ⅶ外,皆为首次从该属植物中发现。

Objective To study the chemical constituents in the whole herb of Dicliptera chinensis.Methods Separation and purification were conducted by silica gel column chromatographic and preparative TLC methods,the structures were identified by IR,NMR,and MS.Results Thirteen compounds were isolated from petroleum ester extract fraction.Their structures were identified as hexatriacontanol(Ⅰ),stearic acid(Ⅱ),lupenone(Ⅲ),lupeol(Ⅳ),4-sitost-4-en-3-one(Ⅴ),stigmast-5-en-7-oxo-3β-yl palmitate(Ⅵ),β-sitosterol(Ⅶ),oleanolic acid(Ⅷ),3β,6β-stigmast-4-en-3,6-diol(Ⅸ),6β-hydroxy-stigmast-4-en-3-one(Ⅹ),3β-hydroxy-stigmast-5-en-7-one(Ⅺ),dehydrovomifoliol(ⅩⅡ),and vomifoliol(ⅩⅢ).Conclusion All the compounds except Ⅱ and Ⅶ are obtained from the plants of Dicliptera Juss.for the first time.