目的研究盾叶薯蓣的水溶性化学成分,寻找活性物质。方法用系统溶剂提取,色谱法分离,光谱法鉴定结构,如:¹H-NMR、¹³C-NMR、¹³⁵DEPT、HMQC、HMBC、TOCSY。结果从盾叶薯蓣的水溶液中分离到一个薯蓣皂苷、一个苯苷类化合物、一个生物碱类化合物。薯蓣皂苷经测定分析,鉴定为26-O-(β-D-葡萄糖)-(25R)-furost-5-en-3β,26-diol-22-OMe-3-O-{α-L-鼠李糖-(1→4)-[β-D-葡萄糖-(1→3)-β-D-葡萄糖-(1→2)]-β-D-葡萄糖}。结论经文献检索为一新化合物,命名为盾叶薯蓣皂苷E(zingierenin E),另两个化合物在盾叶薯蓣中为首次报道。

Objective To study water-soluble constituents of Dioscorea zingiberensis in order to seek active components. Methods Various chromatographic techniques were used to isolate the constituents. Structures of compounds were elucidated by spectroscopic analyses of ¹H-NMR, ¹³C-NMR, ¹³⁵DEPT, HMQC, HMBC, and TOCSY. Results One new steroidal saponin was isolated and identified as 26-0-(β-D-glucopyranosyl)-(25R)-furost-5-en-3β, 26-diol-22-OMe-3-0-｛α-L-rhamnopyranosyl-(1→4)-[β-D-glucopyranosl-(1→3)-β-D-glucopyranosl-(1→2)]-β-D-glucopyranoside｝. Conclusion The compound is a novel compound named as zingierenin E. The other two compounds are reported for the first time from D. zingiberensis.