目的 研究大孔吸附树脂富集、纯化金银花中总有机酸的工艺条件参数。方法 以静态饱和吸附量、静态洗脱率为考察指标,比较了6种大孔吸附树脂分离、纯化金银花总有机酸的工艺。以总有机酸收率和质量分数为指标,对最佳树脂吸附工艺条件进行了筛选。结果 在考察的6种树脂中,HPD100型树脂具有最佳的吸附及洗脱参数。结论 本实验所筛选出的HPD100型树脂综合性能较好,适于金银花总有机酸的分离纯化。

Objective To investigate the technological parameters in the purification process of total organic acids from the immature flower of Lonicera japonica with macroporous resins. Methods Taking static saturated capacity of adsorption and static elution ratio as indexes，six types of macroporous adsorption resins were studied and compared to select the optimum macroporous resins. The technical process for purification of total organic acids from the immature flower of L.japonica with the optimum macroporous resin was screened by the yield and purity of total organic acids .Results The HPD100-type macroporous resin had the optimum adsorption and elution parameters. Conclusion The HPD100-type macroporous resin shows better comprehensive property and can be used to isolate and purify the total organic acids from the immature flower of L.japonica