目的研究川芎Ligusticum chuanxiong干燥根茎中的多糖组分。方法采用DEAE-纤维素柱色谱和凝胶渗透色谱分离纯化，化学和光谱方法分析其结构特征。结果从川芎水提物中分级得到4个均一多糖组分LCP-1、LCP-2、LCP-3和LCP-4，其相对分子质量分别为3.1×10⁴、5.2×10⁴、9.0×10⁴、3.6×10⁴，四者均为结构复杂的多糖组分。结论首次从川芎中分离得到LCP-1、LCP-2、LCP-3和LCP-4 4种杂多糖。

Objective To study the polysaccharides from dried rhizome of Ligusticum chuanxiong. Methods DEAE-Cellulose and gel-filtration chromatography were used to isolate and purify the polysaccharides, whose structures were characterized by chemical and spectral methods. Results Four homogeneous polysaccharides, named LCP-1,LCP-2,LCP-3,and LCP-4 were obtained from the water extract of L.chuanxiong. Four structures were investigated to be complicated polysaccharied fractions,with the molecular weights of 3.1×10⁴,5.2×10⁴,9.0×10⁴,and 3.6×10⁴, respectively, then estimated by GPC. Conclusion The four polysaccharides are obtained from this plant for the first time.

国家自然科学基金资助项目(20175012)