目的对络石藤中的三萜类化合物进行分离鉴定。方法采用硅胶、反相硅胶、Sephadex LH-20等柱色谱方法进行分离,NM R等波谱学方法进行结构鉴定。结果从络石藤中分离鉴定8个三萜类化合物:络石苷F(tra-che losperos ide F,Ⅰ)、络石苷B-1(trache losperos ide B-1,Ⅱ)、络石苷D-1(trache losperos ide D-1,Ⅲ)、络石苷E-1(trache losperos ide E-1,Ⅳ)、3-βO-D-g lucopyranos ide qu inov ic ac id(Ⅴ)、3β-O--βD-g lucopyrano isde qu inov ic ac id27-O--βD-g lucopyranosy l ester(Ⅵ)、3β-O--βD-g lucopyranos ide c incho lic ac id 27-O--βD-g lucopyranosy l ester(Ⅶ)、络石苷元B(trache losperogen in B,Ⅷ)。结论Ⅰ为新化合物,其余均为首次从该植物中分离得到。

Objective To study the triterpenoids from the canes with leaves of Trachelospermum jasminoides.Methods The compounds were separated and purified by column chromatography with silica gel,RP-C₁₈,Sephadex LH-20 and identified by IR,MS,NMR,and 2D-NMR.Results Eight triterpenoids were identified as: trachelosperoside F(Ⅰ),trachelosperoside B-1(Ⅱ),trachelosperoside D-1(Ⅲ),trachelosperoside E-1(Ⅳ),3β-O-D-glucopyranoside quinovic acid(Ⅴ),3β-O-β-D-glucopyranoisde quinovic acid 27-O-β-D-glucopyranosyl ester(Ⅵ),3β-O-β-D-glucopyranoside cincholic acid 27-O-β-D-glucopyranosyl ester(Ⅶ),trachelosperogenin B(Ⅷ),respectively.Conclusion Compound Ⅰ is a new compound and compounds Ⅱ-Ⅷ are isolated from this plant for the first time.

湖州市自然科学基金资助项目(2004-20)