竹黄无性型菌株产竹红菌素的研究

陈佳佳; 李兆兰; 焦庆才; CHEN Jia-jia; LI Zhao-lan; JIAO Qing-cai

温馨提示：建议您使用Chrome80、火狐74+、IE9+浏览器，当您的浏览器版本过低，可能会影响部分功能正常使用。

主办：天津药物研究院中国药学会

微信公众号

网站二维码

首页 > 过刊浏览>2006年第卷第1期 >2006(1):48-50

竹黄无性型菌株产竹红菌素的研究

Hypocrellins produced by anam orphosis fermentation of Shiraia bambusicola

发布日期：2015-01-06

摘要
图/表
访问统计
PDF预览
参考文献
相似文献
引证文献
附件

[关键词]

[摘要]

目的获得能稳定产生竹红菌素的竹黄无性型菌株，通过人工培育获得其活性成分竹红菌甲素。结论通过组织分离，从野生竹黄子座中分离筛选出无性型菌株0258，进行人工条件下的发酵培养。对其发酵产物进行提取、分离和纯化，通过理化性质测定和波谱(UV/VIS、IR、MS)技术进行结构鉴定。结果从竹黄子实体分离筛选到一株无性型菌株0258，其能产生稳定的竹红菌甲素。结论首次获得稳定产生竹红菌素的竹黄无性型菌株，解决了竹黄人工培育的种源问题，使竹红菌素的工业化生产成为可能。

[Key word]

[Abstract]

Objective To obtain anamorphosis of Shiraia bambusicola producing the component,hypocrellin A effectively.Methods A strain was isolated from the fruit of S.bambusicola by separating its hypha and was cultured by solid-state fermentation.One of the pure chemical compounds isolated from the stroma of wild S.bambusicola was studied on the basis of UV/VIS,IR,MS spectrometric analysis and physicochemical constants.Results The pigment is proved to be hypocrellin A.The isolate was determined as the stable anamorphosis strain 0258 of S.bambusicola.Conclusion A namorphosis strain of S.bambusicola is obtained and precisely appraised for the first time.This study will provide basis for the future massively industrialized hypocrellin production.

[中图分类号]

[基金项目]

国家技术创新基金资助项目(02CJ-13-01-16)

更多...

更多...