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[摘要]
目的研究石蒜科植物花朱顶红中非生物碱类成分.方法采用大孔树脂、硅胶、ODS柱色谱分离纯化,经理化常数、光谱学方法鉴定结构.结果分离得到了5个葡糖鞘脂类成分,其结构分别鉴定为(2S,3R,4E,8Z)-2-[(2R-2-羟基十六酰)氨基]-4,8-十八二烯-1,3-二醇1-O-β-D-吡喃葡萄糖苷(Ⅰ)、(2S,3R,4E, 8E)-2-[(2R-2-羟基十六酰)氨基]-4,8-十八二烯-1,3-二醇1-O-β-D-吡喃葡萄糖苷(Ⅱ)、(2S,3R,4E,8Z)-2-[(2R-2-羟基十八酰)氨基]-4,8-十八二烯-1,3-二醇1-O-β-D-吡喃葡萄糖苷(Ⅲ)、(2S,3R,4E,8E)-2-[(2R-2-羟基十八酰)氨基]-4,8-十八二烯-1,3-二醇1-O-β-D-吡喃葡萄糖苷(Ⅳ)、(2S,3R,4E,8Z)-2-[(2R-2-羟基二十酰)氨基]-4,8-十八二烯-1,3-二醇1-O-β-D-吡喃葡萄糖苷(V).结论它们均为首次从花朱顶红中分得.
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[Abstract]
Objective To investigate the non-alkaloid constituent ofHippeastrun vittatum(Amarylli-daceae).Methods Solvent extraction and column chromatography were used to isolate the non-alkaloid constituents,and physicochemical constants and spectros-copic analysis were employed for structural elucidation.Results Five glycosphingosilipids were isolated,and their structures were elucidated to be(2S,3R,4E,8Z)-2-[(2R-2-hydroxyhexadecanoyl)amido]-4,8-octadecadiene-1,3-diol 1-O-β-D-glucopyranoside(I)(2S,3R, 4E,8E)-2-[(2R-2-hydroxyhexadecanoyl)amido]-4,8-octadecadiene-1,3-diol 1-O-β-D-glucopyranoside(Ⅱ),(2S,3R,4E,8Z)-2-[(2R-2-hydroxyoc-tadecanoyl)amidol-4,8-octadecadiene-1,3-diol 1-O-β-D-glucopyranoside(m),(2S,3R,4E,8E)-2-[(2R-2-hydroxyoctadecanoyl)amidol-4,8-octa-decadiene-1,3-diol 1-O-β-D-glucopyranoside (Ⅳ),(2S,3R,4E,8z)-2-[(2R-2-hydroxyeicosadecanoyl)amidol-4,8-octadecadiene-1,3-diol 1-O-β-D-91ucopyranoside(V),respectively.Conclusion They are all isolated from the fresh bulbs ofH.vittatum for the first time.
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