目的 研究六角莲Dysosma pleiantha的化学成分.方法 用1%盐酸沉淀出酸性树脂后再采用反复硅胶柱色谱分离纯化,通过理化常数测定和光谱分析鉴定其化学结构.结果 从六角莲的酸性树脂中分离鉴定了10个化合物,其中5个四氢萘类木脂素化合物:鬼臼酮(Ⅰ)、脱氢鬼臼毒素(Ⅱ)、鬼臼毒素(Ⅲ)、4′-去甲基鬼臼毒素(Ⅳ)、4′-去甲基脱氢鬼臼毒素(Ⅴ);两个黄酮类化合物:山柰酚(Ⅵ)、槲皮素(Ⅶ);以及正十六烷酸(Ⅷ)、β-谷甾醇(Ⅸ)和胡萝卜苷(Ⅹ).结论 化合物是新化合物,化合物β为首次从该属植物中分离得到,其他化合物均为首次从该植物中分离得到.

Objective To study the chemical constituents of Dysosma pleianthaMethods Acidicresins were precipitated by 1％HCl solution,then the constituents were isolated and purified on repeated silica gel column.They were identified and structurally elucidated by physicochemical constants and spec-tral analysisResults Ten compounds were obtained and identified：podophyllotoxone(Ⅰ),dehy-dropodophyllotoxin(Ⅱ), podophyllotoxin(Ⅲ),4'-demethylpodophyllotoxin (Ⅳ),4'-demethyldehy dropodophyllotoxin(Ⅴ),kaempferol(Ⅵ),quercetin(Ⅶ),n-hexadecanoic acid(Ⅷ),β-sitosterol(Ⅸ),and daucosterol(Ⅹ)Conclusion Compound Ⅴ is a new compound,compoundsⅦ-Ⅹ are first separated from the plants of Dysosma Woodson and other compounds are first separated from Dpleiantha.