目的探讨不同炮制方法对泽泻中泽泻醇B23-乙酸酯的影响。方法采用RP-HPLC法。反相HypersilODSC18柱(200mm×4.6mm,5μm),以乙腈-水(70∶30)为流动相,检测波长为208nm。结果樟帮麸炒法的质量分数为0.1565%,生品为0.155%,而其他炮制品质量分数均低于生品。结论不同炮制方法、辅料对泽泻各炮制品中泽泻醇B23-乙酸酯含量有一定的影响。

Objective To investigate the effects of different processing methods on alisol B23-acetate in Alisma orientale. Methods The contents of alisol B23-acetate were determined by RP-HPLC. Chromatographic conditions included Hypersil C_(18) column, mobile phase: acetonitrile-water (70∶30), detecting wavelength: 208 nm. Results The content of alisol B23-acetate in processing sample stir-baked with bran by the method of Zhangbang was 0.156 5%, the crude sample was 0.155%, and the content of alisol B23-acetate in other processing samples was less than the crude sample. Conclusion Different processing methods and ajuvants show a certain influence on the contents of alisol B23-acetate in its different processed products.