目的 研究超临界 CO₂ 流体萃取 (SFE- CO₂ )血竭中抑制α-葡萄糖苷酶有效成分的工艺条件。方法 采用单因素法 ,探讨了压力、温度、时间和 CO₂ 流量对血竭萃余率和抑制 α-葡萄糖苷酶活力提高率的影响。结果 最佳工艺条件为萃取压力 15 MPa,温度 4 5℃ ,CO₂ 流量为 30 kg/ h,时间 2h。优于传统的索氏抽提。结论 SFE- CO₂ 工艺用于血竭中有效成分提取 ,萃余率和抑制 α-葡萄糖苷酶活力提高率均有较大程度提高

Object To study the technology of supercritical CO₂ extraction of effective components from Dragon's Blood which has the inhibiting function on α-glucosidase. Methods The influence of the extraction pressure, temperature, time and fluid velocity on surplus extraction rate and the improvement of inhibition was mainly discussed. Results The optimal experimental parameters were 15 MPa extraction pressure, 45 ℃ extraction temperature, 30 kg/h fluid velocity and 2 h extraction time. Conclusion The results show that SFE-CO₂ can enormously increase the surplus extraction rate and the inhibitory activities on α-glucosidase

上海市科技发展基金资助项目(02DZ9118)