目的优选交泰丸方药的提取工艺。方法以小檗碱、肉桂酸、总生物碱、挥发油、干浸膏为指标,在药材粒度、溶剂量、煎提温度、滤过、浓缩等条件相同的前提下,对半仿生提取法(SBE法)、水提取法(WE法)、半仿生提取醇沉法(SBAE法)、水提取醇沉法(WAE法)进行比较研究。结果5个指标综合评价Y值为:SBE法>WE法>SBAE法>WAE法。结论交泰丸方药的提取法以SBE法为佳。

Object To evaluate the extracting technology of Jiaotai Pill components. Methods Four methods - the semi bionic extraction (SBE), the water extraction (WE), the semi bionic extraction by precipitation with alcohol (SBAE), and the water extraction by precipitation with alcohol (WAE) were used to extract Jiaotai Pill component, with berberine, cinnamic acid, total alkaloids, volatile oil and dried extract taken as the markers and to study the four methods under the same conditions of drug granularity, solvent amount, decocting temperature, filtration, concentration, etc. Results The comprehensive values Y were SBEWESBAEWAE. Conclusion SBE method is better than the other three methods in the extraction of Jiaotai Pill components.

山东省自然基金资助项目(Q00C05)