[关键词]
[摘要]
目的 研究地骨皮 (枸杞 Lycium chinense根皮 )的化学成分。方法 利用各种色谱技术进行分离纯化 ,根据化合物的理化性质和光谱数据进行结构鉴定。结果 分离得到 5个化合物 ,分别为 :香草酸 (vanillic acid, )、芹菜素 (apigenin, )、蒙花苷 (linarin, )、紫丁香酸葡萄糖苷 (glucosyringic acid, )及地骨皮苷甲 (digupigan A, )。结论 化合物 为新化合物 ,化合物 ～ 均为首次从地骨皮中分得
[Key word]
[Abstract]
Objective<\b> To study the chemical constituents from the root barks of Lycium chinense. Methods<\b> The chemical constituents of EtOAc fraction from 95% ethanol extract of L. chinense were isolated and purified by chromatography on silica gel, Sephadex LH-20, and ODS. Their chemical structures were identified on the basis of physicochemical properties and spectroscopic data. Results<\b> Twelve compounds were isolated and identified as N-trans-coumaroyltyramine (1), N-trans-feruloyltyramine (2), dihydro-N-caffeoyltyramine (3), apigenin (4), ferulic acid (5), p-hydroxycinnamic acid (6), 3-hydroxy-1-(4-hydroxyphenyl)-1- propanone (7), 3, 4-dihydroxybenzenepropionic acid (8), 3, 4-dihydroxybenzenepropionic acid methyl ester (9), p-hydroxy-benzoic acid (10), 4-methoxy salicylic acid (11), and nicotinic acid (12). Conclusion<\b> Compounds 8 and 9 are two new natural products, and compounds 1, 6, 11, and 12 are obtained from this plant for the first time.
[中图分类号]
[基金项目]
“九五”国家攻关重点项目 (99-92 9-0 1-3 1)
