目的 探讨从甘草中提取甘草次酸的工艺。方法 采用超临界 CO2 萃取法 ,并与索氏提取法、超声法进行比较。结果 超临界 CO2 萃取法的最佳工艺条件为:压力 30 MPa,原料粒度 70目 ,夹带剂为 80 %乙醇 ,萃取温度4 5℃ ,萃取时间 2 h。结论 从甘草生药中提取含量较少的甘草次酸 ,超临界萃取法较其他几种提取方法具有明显的优势。

Object To establish the process of supercritical CO 2 extraction of glycyrrhetic acid from Glycyrrhiza uralensis Fisch.. Methods The comparison Methods among supercritical CO 2 extraction, Soxhleth extraction and ultrasonic extraction were conducted. Results The optimized supercritical CO 2 extraction conditions were 30 MPa, pressure; 70 meshes, granularity of material; 80% ethanol, modifying agent; 45 ℃, extraction temperature; 2 hours, extraction time. Conclusion The results show that supercritical CO 2 extraction has an advantage over any other extractions of glycyrrhetic acid from G. uralensis.