目的 研究北沙参的化学成分。方法 用硅胶柱层析,通过光谱数据分析确定化合物的结构。结果 从北沙参乙醇提取物的乙酸乙酯萃取部分分离得到 8个化合物,分别鉴定为法卡林二醇 (falcalindiol,Ⅰ)、(8E)十七碳 -1,8-二烯 - 4,6 -二炔 - 3,10 -二醇 [(8E) - 1,8- heptadecadiene- 4,6 - diyne- 3,10 - diol,Ⅱ)、佛手柑内酯 (bergapten,Ⅲ)、蛇床克尼狄林 (cnidilin,Ⅳ)、花椒毒素 (xanthotoxin,Ⅴ)、水杨酸 (salicylic acid,Ⅵ)、香草酸 (vanillic acid,Ⅶ)、阿魏酸(ferulic acid,Ⅷ)。结论 化合物Ⅱ和Ⅵ～Ⅷ为首次从该植物中分离得到。

Object To study the chemical constituents of the underground part of Glehnia littoralis Fr.Schimidt ex Miq.Methods Eight compounds were isolated from EtOAc-soluble fraction of ethanol extract of G.littoralis by repeated chromatography over silica gel.Their structures were determined on the basis of their spectral data.Results They were identified as falcalindiol (Ⅰ), (8E)-1, 8-heptadecadiene-4, 6-diyne-3, 10-diol (Ⅱ), bergapten (Ⅲ), cnidilin (Ⅳ), xanthotoxin (Ⅴ), salicylic acid (Ⅵ), vanillic acid (Ⅶ), ferulic acid (Ⅷ).Conclusion Compounds Ⅱ and Ⅵ-Ⅷ were isolated from this plant for the first time.