目的 研究海藻多糖的抗肿瘤作用机制。方法 采用荧光探针 DPH法,观察海藻多糖对 S₁₈₀ 和 H₂₂ 小鼠细胞膜流动性的影响。结果 海藻多糖可升高 S₁₈₀ 荷瘤小鼠肿瘤细胞的膜流动性,降低 H₂₂ 荷瘤小鼠肿瘤细胞膜流动性。结论 海藻多糖可恢复肿瘤细胞膜流动性至正常细胞膜流动性而达到抗肿瘤的作用。

Object To study the antitumor mechanism of sea algae polysaccharide (SP). Methods The membrane fluidity of the S 180 and H 22 mice was observed by DPH fluorescent probe method. Results SP could increase the membrance fluidity of the S 180 and decrease that of the H 22 . Conclusion SP showed the antitumor effect through returning the tumor cell membrance fluidity to the normal one.

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