目的 研究传统中药天师栗 Aesculus wilsonii种子的皂苷类成分。方法 利用大孔树脂柱色谱、高效液相色谱等方法进行分离和纯化,根据化合物的波谱数据、酸和 /或水解产物鉴定其结构。结果 从天师栗种子的 70 %乙醇提取物中分得 8个化合物,分别鉴定为七叶树皂苷 (escins) a、 b、 a和异七叶树皂苷 (isoescins) a, a, b, b, a。结论 8个化合物均为首次从天师栗种子中分得。

Object To study the saponin constituents from the seeds of Aesculus wilsonii Rehd Methods Compounds were separated and purified by macroreticular resin column chromatography and HPLC chromatography Their structures were elucidated by spectroscopic, acid and / or hydrolysate analysis Results Eight compounds were isolated from 70% ethanolic extracts of the seeds They were identified as escins Ⅰa, Ⅰb, Ⅲa and isoescins Ⅰa, Ⅱa, Ⅰb, Ⅱb, Ⅲa Conclusion Mentioned compounds were obtained from the seeds of A wilsonii for the first time

国家自然科学基金资助项目(No.29972004)