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[摘要]
目的 为了寻找抗肿瘤的活性成分。方法 利用溶剂法和色谱法对绿海葵进行了研究。结果 分离得到5个核苷,经波谱学解析鉴定为2-羟基嘌呤核苷(Ⅰ),脱氧肌苷(Ⅱ),1-甲基黄嘌呤核苷(Ⅲ),脱氧鸟苷(Ⅳ),脱氧核糖胸腺嘧啶(Ⅴ)。结论 Ⅲ为一新天然产物,其余均为海洋生物中首次发现。
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[Abstract]
Object To study the chemical constituents of sea anemone, Anthopleura stell Verrill.Methods The chemical constituents were isolated and purified by chromatographic methods and their structures elucidated by chemical evidences and spectra data.Results 5 nucleosides were obtained and identified from the ethanolic extract as 2-hydroxy purine (Ⅰ); deoxyinosine (Ⅱ); 1-methylxanthosine (Ⅲ); deoxyguanosine (Ⅳ), and deoxyribo-thymidine (Ⅴ).Conclusion Compound Ⅲ was a new natural product, while the others were found from sea anemone for the first time.
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